EDM producer Diplo turns in a remix of Lorde's tennis court named for furry tennis legend Andre Agassi.
Find out if it's in your court, AFTER THE JUMP...
Researchers at Temple University have successfully managed to eliminate HIV from infected human cell cultures according to a recently released study. Most current HIV treatments target the various means through which HIV integrates itself into healthy host cells in order replicate itself. The team at Temple, however, employed a form of advanced gene therapy in order to render HIV-infected cells completely HIV-free. From the team’s press release:
When deployed, a combination of a DNA-snipping enzyme called a nuclease and a targeting strand of RNA called a guide RNA (gRNA) hunt down the viral genome and excise the HIV-1 DNA. From there, the cell's gene repair machinery takes over, soldering the loose ends of the genome back together – resulting in virus-free cells.
Treatments capable of removing HIV from infected cells have long since been a goal for those within the HIV/AIDS research community. While antiretrovirals are able to suppress the viral loads in HIV positive people, interruptions in treatment give the virus the chance to proliferate, sometimes with dangerous consequences such as cardiomyopathy, kidney disease, and neurocognitive disorders.
"These problems are often exacerbated by the toxic drugs that must be taken to control the virus," explained Dr. Kamel Khalili. "Since HIV-1 is never cleared by the immune system, removal of the virus is required in order to cure the disease."
This development comes just days after a report published at the 20th International AIDS Conference announced that HIV infection rates in general have dropped here in the U.S. The one population observed to have experienced a rise in infection rates were gay and bisexual men.
Controlled tests with the gene therapy method have proven to be successful, but Khalili says that his team still faces a number of significant challenges before the treatment is ready for patient trials. In order to be completely effective the molecular agents responsible for disabling HIV’s replication process would have to be delivered to every cell in an infected individual’s body. Moreover, the strain of HIV that the treatment has proved effective against, HIV-1, is prone to mutation, further complicating the therapy’s effectiveness outside of controlled environments.
"We are working on a number of strategies so we can take the construct into preclinical studies," Khalili said. "We want to eradicate every single copy of HIV-1 from the patient. That will cure AIDS. I think this technology is the way we can do it."
Watch Temple University's video announcing the research breakthrough AFTER THE JUMP...
Openly Gay Former NFL Player David Kopay Remembers His Scandalous Coming Out, Celebrates Michael Sam: VIDEO
In 1975, David Kopay became the first NFL player, current or former, to come out publicly in the Washington Star. It was a stunning moment for sports, and he later revealed even more--including a one night stand with former Redskin player Jerry Smith--in his memoir, The David Kopay Story. Now, nearly forty years later, Kopay is one of many who are welcoming Michael Sam, the first openly gay player to be drafted into the NFL, with open (but concerned) arms.
The Hollywood Reporter recently wrote about Kopay's experience:
"I was desperate," he says. "I was totally, 'What am I going to do with my life? Can I make a difference?' " He'd hoped his tale...would encourage other pro athletes to come out. But years turned to decades and few had followed suit. Meeting Sam, the gifted defensive end who shattered the last civil rights hurdle in pro sports when he kissed his boyfriend after being drafted by the St. Louis Rams in May, came as more than just a passing thrill. It was the culmination of a life's work.
One need only consider current attitudes toward gays in sports -- when a celebratory kiss between men can result in an uproar -- to grasp just how shocking Kopay's admission was for the 1970s. And yet somehow his remarkable story has faded over the years. According to columnist Will Leitch, founding editor of Deadspin, that largely is due to Kopay being eons ahead of his time. "I think it was honestly too early," says Leitch. "It was 1975. In four years, Al Pacino would be making Cruising. People were not ready for an NFL player being gay at all."
And neither were Kopay's family and friends. Married at the time, he got divorced and was excommunicated by his Catholic mother; she left him with the kind parting words, "I created you and I can kill you." Kopay moved to San Francisco, rubbing shoulders with Harvey Milk and living with Armistead Maupin, then to Los Angeles where he has lived since.
Kopay swims laps daily at nearby Occidental College, regularly hits the Rose Bowl flea market and enjoys attending NFL alumni games and serving as honorary ambassador to the Gay Games. He lives alone, his garage lined with memory boards filled with photos of debauched days spent in New Orleans. Whenever he speaks of past loves, they are invariably of the unrequited kind.
It is understandable then that Sam's decision to kiss his boyfriend after receiving his draft call would dredge up proud but conflicted emotions for Kopay.
"I was a bit unnerved," Kopay admits of watching Sam plant a passionate smooch on boyfriend Vito Cammisano, the pair later smearing cake on each other's faces. "I'm old school, you know? Certainly I felt he had a right to kiss his boyfriend and I was really glad he did. But I was not so happy with the cake in the face. It was a little bit over the top. I just worried about him like, 'Oh, what's the fuss that this is going to cause?'"
Hopefully relatively little, and Kopay seems to admit that he is of a different era. He also took the first, and perhaps bravest step of all.
"I think it was the first brick removed from the wall of homophobia," says Cyd Zeigler, the co-founder of Outsports.com. "When Kopay came out, the gay community was just beginning to find its identity. For a portion that didn't associate with the stereotypical gay identity, Dave's honesty was life-changing. I'm sure it saved lives."
Check out an interview with Kopay, AFTER THE JUMP...
Adam Lambert gave Jake Shears something he was craving.
Writes Shears on Instagram: "Finally got stuffed by @adamlambert".
Finger lickin' good.Sphere: Related Content
Former NFL coach-turned-NBC analyst Tony Dungy said this week that he would not have taken the NFL’s first openly gay player Michael Sam onto a team, “Not because I don’t believe Michael Sam should have a chance to play, but I wouldn’t want to deal with all of it.”
Soon after, commentator Keith Olbermann took Dungy to task by mentioning that in 2007 Dungy supported an Indiana same-sex marriage ban, and in 2009 Dungy also argued for the re-admission of dog-fighter Michael Vick into the NFL.
Considering his stance on Vick, The Orlando Sentinel’s George Diaz points out Dugger’s hypocrisy:
Vick’s crime was dog-fighting. Those who didn’t make the cut were shot, beaten and electrocuted. Three dogs were hanged, according to a report by the USDA inspector general, “by placing a nylon cord over a 2 x 4 that was nailed to two trees.” Three more dogs drowned after Vick’s crew put their heads in a 5 gallon bucket of water…
But Dungy has a serious problem on his hands trying to explain why a gay player is a bigger distraction as a guy who killed dogs. Since, you know, that wasn't a big story. #sarcasm…
Sam’s crime? He kissed a guy. On National TV, the day he was drafted by the St. Louis Rams…
“I believe in second chances for people who admit their mistakes and are committed to changing,” Dungy said…
But apparently Tony Dungy is not a big believer in first chances for someone who has made no mistakes, and all he is asking for is an opportunity.
In an e-mail statement responding to Dungy’s comments, GLAAD President and CEO Sarah Kate Ellis said, “Talent is not a distraction. Michael Sam is first and foremost an excellent football player. That Tony Dungy can only see Michael Sam for his sexual orientation reflects how far out of touch Dungy has fallen with the NFL, which values a player because of his skill, not because of who he loves.”
Watch Olbermann's takedown of Dungy AFTER THE JUMP...
Duane Youngblood, author of Freedom From Homosexuality: No Longer Living The Lie and owner of the Higher Call World Outreach Church in Homestead, Pennsylvania, has been arrested on suspicion of sexually assaulting a teenager.
The boy, now aged 21, told police that the pastor sexually abused him between 2009 and 2001 while Youngblood was supposed to be counseling him, reports CBS Pittsburgh. Youngblood is also accused of showing the teen an adult movie on his computer.
The pastor reportedly asked his victim not to tell his mother “because he didn’t want to get into trouble.”
In his 2006 book, Youngblood "shares insights and truth to help anyone struggling with perversions find a place of forgiveness and deliverance in God."
Neighbors say the pastor, who is a registered sex offender, is married with multiple children.
In 2006, Youngblood was sentenced to one year of intermediate punishment and seven years’ probation after he was found guilty of molesting a 15-year-old boy whom he was also counseling.Sphere: Related Content