Poppers Linked To Uptick of Sudden Vision Loss

A sharp uptick in diagnoses of sudden maculopathy, a drastic impairment of vision, are being attributed to the use of poppers according to Reuters. While it is unclear how exactly poppers are physiologically causing the damage, cases of rapid vision loss following their use are becoming more and more common.

POPPERS_MEGARUSH3_1338907917Upon examining a man in his early 30s who reported using poppers recreationally Dr. Anna Gruener, an opthamologist at Guy’s and St Mary’s Foundation Trust, observed  uncharacteristic yellow spots on his fovea, a section of the eye for sharp central vision. The man reported significant loss of vision even after ceasing to use poppers for six months.

“Over the past 18 months or so I have come across almost 10 patients with poppers maculopathy, whilst several years ago I had not even heard of the condition, same with a lot of my colleagues,” Dr. Gruener told Reuters Health. “I felt it was important to raise the issue and increase awareness.”

Isobutyl nitrate, the primary nitrate liquid in poppers, was banned by the EU in 2007 amidst concerns about their potential health impacts. Gruener suspects isopropyl nitrate, introduced to replace the old chemical composition may potentially be to blame. Reports of “poppers maculopathy” began to surface in France in 2010 and 2011 before appearing in the U.K. in 2012.

Poppers, most commonly used as a recreational aphrodisiac, have existed in something of legal limbo for many years.

Amyl nitrate, sometimes used to treat angina and cyanide poisoning, was banned from recreational use (as poppers) in 1969 in the U.S. Since then, popper manufacturers have continuously tweaked the specific kind of nitrate compounds in their products as previous combinations are outlawed.

Comments

  1. Jay says

    I’m sure many gays will see this as a plus. Not only it gives you a head rush, it will also enable sensory deprivation for a more intense experience lol.

  2. Ken says

    If this were true, wouldn’t it have become evident years ago? Poppers have been around a very long time, and have been used by, oh, millions of people. Yet we are just now hearing of this.

  3. NwYrkr says

    Samuel, that appears to be the case per the article. New chemical compound has only been in use since 2007.

    “Isobutyl nitrate, the primary nitrate liquid in poppers, was banned by the EU in 2007 amidst concerns about their potential health impacts. Gruener suspects isopropyl nitrate, introduced to replace the old chemical composition may potentially be to blame. Reports of “poppers maculopathy” began to surface in France in 2010 and 2011 before appearing in the U.K. in 2012″

  4. Bill says

    I wish somebody could explain what the desirable effect of poppers is. Never did anything for me, at least nothing that I found enjoyable. Some of the comments here reflect the denial of someone who doesn’t want to give up something. Sorta like the boy who, when told that masturbation causes blindness, asks; “Can I do it until I need glasses?”

  5. Zlick says

    The formula has been changed a few times. Our trusted supplier recently told us of a recent change, and my bf bought out his small supply of the old formula (even though we don’t use them all that often … so we’ve essentially got a lifetime supply of what will be fondly known as the old stuff once everyone goes blind from the new stuff.)

    I’m sure poppers are not for everybody, and for me they’re not nearly for every time. But they have both a strong enhancement effect AND a minor aphrodisiac effect, imo. I certainly don’t find it credible they destroy brain cells – especially in light of the ASAP Science video posted on this site just a couple of days ago which debunked the myth that alcohol destroys brain cells.

    That said, constant or extended use doesn’t seem like a good health idea to me. In my less cautious youth, I think I did overdo them at one point.

  6. Tom says

    Sounds like Retchard has some big issues with poppers. Funny.
    Fun occasional enhancement to sex. But poppers were better pre-2007.
    Anything in moderation. Live your life, be free.

  7. The Milkman says

    If you read the article from Dr. Gruener published in Lancet, it’s really nothing more than a case study. The authors claim “probable” causality, but present no evidence supporting their claims. A quick review of other articles on the subject revealed similar statements of concern, but no discussion of the mechanism by which poppers might cause the suspected injury, let alone a blinded, placebo-controlled trial. So all these claims right now are based on correlation or conjecture. The claims might end up being true, but we can’t know that yet based on the evidence that’s available. Further, there are other conditions such as photic maculopathy which are better-researched and have identical clinical presentations… and given the environments in which poppers are used, photic maculopathy may be the actual culprit here. Basically, the evidence is simply not strong enough to support the identification of a causal relationship.

    That said, if one wants to discontinue using poppers out of an abundance of caution, that’s perfectly fine. But the literature simply doesn’t support Dr. Gruener’s claims of causality.

  8. boo says

    Thank You Milkman…for the reasoned and logical insight. Otherwise we might have to suffer, yet more, of “Retchard”s hysterical outburst.Some of these bitches appear to have zero life experience,and still find justification for their ignorance and judgmental theories.

  9. MickyFlip says

    Honestly, I’m biased about poppers considering all it does is give me a headache. So I’m not a huge fan anyways. I’d rather have a bowl of green trees than poppers. So now that we covered the green bud and currently poppers. When are we going to get into Adderall?

  10. calpoidog says

    I’ve never understood why anyone would want to purposely inhale a chemical into their lungs that doesn’t belong there, regardless of the momentary effects.

  11. northoftheborderguy says

    macular degeneration has multiple causes.. and not just age related. There may be a correlation, there may not be. Maybe they’re going to suntan booths and keeping their eyes open without covers. anything is possible. As for braincells.. what chemical doesn’t kill braincells. even pot does that.

  12. Just_a_guy says

    “Maybe they’re going to suntan booths and keeping their eyes open without covers.”

    Well, yeah, and maybe the poppers make them less bothered by such harmful activities. And if true, it wouldn’t be the poppers themselves, but what people allow themselves to do without caution on the poppers, that is the culprit. But it doesn’t sound like we know.

  13. Hansel Currywurst says

    Maybe Big Pharma has an inconsequential tweak of the isobutyl nitrate molecule (to skirt the law while making it patentable) ready to roll and they’re expanding their future market by creating a fictitious problem to solve.

    BTW: “Angina” seems like the perfect drag name.

  14. Randy says

    Calpoidog said: “I’ve never understood why anyone would want to purposely inhale a chemical into their lungs that doesn’t belong there, regardless of the momentary effects.”

    I want you to consider how close that is to: “I’ve never understood why anyone would want to purposely insert a penis into their rectum that doesn’t belong there, regardless of the momentary effects.”

    Once you realize what’s wrong with your argument (hint: we were not designed) then come back and try again.

  15. djhollen says

    I stopped using them when I would notice a pale white spot floating right over the center of my vision. It would go away as soon as the effects wore off, but it still was worrying enough to quit. This was back in the late 80’s.

  16. Getyourfactstraight says

    I love poppers. Never had any ill effects, been using them off and on for decades. Nothing like it when you are bottoming for a guy with a nice big one. And orgasms are greatly enhanced. Oh yeah! They have studied poppers looking for ill effects and actually there has been no poof that they cause any harm. I can see if they have been messing with the formula and adding some new crap that there is potential for harm. Which is why they should never have outlawed Amyl, which is used medically for heart patients. All you prudes who don’t understand what a vasodilator is or does but feel you have to give your ignorant opinion should do a little research.

  17. Edgar Carpenter says

    Amyl nitrite, the original drug, was only banned because it was being used a lot during gay sex, and governments wanted to discourage gay sex. It is safe, and does not cause eye, lung, brain or other damage, except when used with the much more recent viagra (mixed with viagra it causes a dangerous drop in blood pressure). If they brought back amyl nitrite, with a clear warning on each bottle not to use it with Viagra and similar hardon drugs, everyone would be much happier and healthier. The stuff sold as poppers since that ban have varied wildly in quality and purity, and have mostly been unhealthy.

  18. DC says

    I have no experience with poppers. I’ve experimented with many drugs in my youth, however, but the only thing I continue to enjoy on occasion is pot. I strive not to judge the behaviors of others given my vices, but see a significant shift in degrees between pot or alcohol and drastically harmful drugs such as meth. Poppers really turn me off, however; they are too reminiscent of huffing. I’ve known a few fools that were all about sniffing glue, huffing butane, or spray paint fumes from paper sacks; they have caused themselves irreparable brain damage. Guys that are crazy for poppers remind me too much of those huffers, so I automatically dismiss them. I don’t want to play around with them, nor even get to know them as people. I do not feel I’m missing out on much of anything. I’m very much into big booty play, as well, and certainly don’t feel the need to inhale who knows what to enjoy getting myself blissfully wrecked.

  19. Bill says

    Yes, Crispy, I am a top. Thanks for the explanation. Now could you please explain why poppers confer some benefit on a bottom with a big cock up his ass? Enquiring Minds Wanna Know!

  20. Cee says

    Guess my comment didn’t post. Poppers can cause vision problems. I know first hand. It happened to me right after I inhaled during a session a couple months ago. I asked my buddy if that ever happened to him. He said no. Guess I’m just unlucky. I know it was the poppers. My eye site is still not the same.

  21. AJ says

    I had to stop using them about two years ago for the same reason, I had a blind spot in the centre of my vision, it caused terrible vertigo and the symptoms lasted for 6-8 months, it was horrendous, I couldn’t read as the letters in the middle of a word used to vanish and it made me so tired at work.

    In banning the origina harmless substance to try and get rid of them they have in effect created a dangerous product.

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