• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • Skip to footer
  • Advertise
  • Contact Us
  • About Towleroad
  • Towleroad on Social Media
  • Privacy Policy

Towleroad Gay News

Gay Blog Towleroad: More than gay news | gay men

  • Body
  • Daily Resist
  • POLITICS
  • Travel
  • Music
  • Theatre
  • Film
  • TV
  • Business
  • Men
  • Marriage Equality
  • Space
  • Trans Rights
  • Books
  • Science
  • Gay Iconography
  • TowleREAD

Scientists Find HIV Receptor That Takes Virus to the Gut

Andy Towle February 12, 2008

Dr. Anthony S. Fauci, reporting in the journal Nature Immunology, says he and a team have discovered a new HIV receptor that may help to develop additional therapies for the disease. The new receptor explains why HIV begins its attack on the immune system in the gut:

Hiv“Dr. Fauci, James Arthos, Claudia Cicala, Elena Martinelli and their colleagues showed that a molecule, integrin alpha-4 beta-7, which naturally directs immune cells to the gut, is also a receptor for H.I.V. A protein on the virus’s envelope, or outer shell, sticks to a molecule in the receptor that is linked specifically to the way CD4 cells home in on the gut, the researchers said. Binding of the virus to the integrin alpha-4 beta 7 molecule stimulates activation of another molecule, LFA-1, which plays a crucial role in the spread of the virus from one cell to another. The actions ultimately lead to destruction of lymph tissue, particularly in the gut. Several other receptor sites for H.I.V. are known. The most important is the CD4 molecule on certain immune cells; the molecule’s role as an H.I.V. receptor was identified in 1984. Two other important receptors, known as CCR5 and CXCR4, were identified in 1996. CCR5 is a normal component of human cells and acts as a doorway for the entry of H.I.V. People who lack it because of a genetic mutation rarely become infected even if they have been exposed to H.I.V. repeatedly. ‘The work we did took nearly two years, and there’s little doubt that what we have found is a new receptor,’ Dr. Fauci said in an interview after giving a lecture here, adding that ‘we certainly have to learn a lot more about it.'”

Scientists Find New Receptor for H.I.V. [nyt]

Topics: News More Posts About: AIDS/HIV, Health, Medicine, News

Related Posts
  • US marks 1 mn Covid deaths, early epicenter New York seeks to move on
  • Almost three times as many died as a result of COVID than officially reported – WHO
  • People with certain health conditions ‘more likely to end their life’
  • Tom Daley and Dustin Lance Black almost missed son’s birth

    Tom Daley and Dustin Lance Black almost missed son’s birth

    Published by BANG Showbiz English Tom Daley and Dustin Lance Black almost missed the birth of their son as they got stuck in traffic on their way to the hospital. The couple – who have been …Read More »
  • Ousted Rep. Madison Cawthorn Calls For ‘Dark MAGA’ To Rise Up, Take Over Political Right

    Ousted Rep. Madison Cawthorn Calls For ‘Dark MAGA’ To Rise Up, Take Over Political Right

      Published by Radar Online   MEGA Fresh off his loss in a primary election in North Carolina, soon-to-be outgoing Republican Rep. Madison Cawthorn is now calling for a new party to form on the right. …Read More »
  • U.S. Justice Department releases $5 million for hotlines to report hate crimes

    U.S. Justice Department releases $5 million for hotlines to report hate crimes

    Published by Reuters WASHINGTON (Reuters) – The U.S. Justice Department will release $5 million for states to establish hotlines to report hate crime, U.S. Attorney General Merrick Garland said on Friday, as a mass shooting in …Read More »
  • Monkeypox Gay Cases Rise; Europe Hits 100 Total; Triggers Emergency WHO  Monkeypox Meeting; Symptoms Mild; Spain Connects Monkeypox virus, Sauna

    Monkeypox Gay Cases Rise; Europe Hits 100 Total; Triggers Emergency WHO Monkeypox Meeting; Symptoms Mild; Spain Connects Monkeypox virus, Sauna

    Published by Reuters By Jennifer Rigby and Natalie Grover LONDON (Reuters) -The World Health Organization was due to hold an emergency meeting on Friday to discuss the recent outbreak of monkeypox, a viral infection more common …Read More »
Previous Post: « Jerry O’Connell’s Crazy ‘End of Writer’s Strike’ Party
Next Post: Maryland Rallies for Marriage Equality at Annapolis Statehouse »

Primary Sidebar

News

  • New York Attorney General Announces Investigations Into Social Media Companies For Role In Buffalo Attack That Left 10 Dead

    New York Attorney General Announces Investigations Into Social Media Companies For Role In Buffalo Attack That Left 10 Dead

  • Former Presidential Advisor Reveals Vladimir Putin Was Constantly ‘Frustrated’ With Donald Trump & ‘Had To Keep Explaining Things’

    Former Presidential Advisor Reveals Vladimir Putin Was Constantly ‘Frustrated’ With Donald Trump & ‘Had To Keep Explaining Things’

  • NYC Congresswoman Alexandria Ocasio-Cortez Confirms Engagement To Longtime Love Riley Roberts

    NYC Congresswoman Alexandria Ocasio-Cortez Confirms Engagement To Longtime Love Riley Roberts

  • Princess Diana’s tiara to headline exhibition at Sotheby’s

    Princess Diana’s tiara to headline exhibition at Sotheby’s

Break

  • Viola Davis was called by director’s maid’s name

    Viola Davis was called by director’s maid’s name

  • Kerry Washington infuriated Scandal co-stars with kiss confession

    Kerry Washington infuriated Scandal co-stars with kiss confession

  • Ryan Reynolds recalls brothers ‘saving’ him from dad’s anger with earrings

    Ryan Reynolds recalls brothers ‘saving’ him from dad’s anger with earrings

  • Upfronts 2022: Every new scripted series picked up by a broadcast network

    Upfronts 2022: Every new scripted series picked up by a broadcast network

RSS Partner Links

  • Song of the Day: 'Push It' by Salt-N-Pepa
  • Saturday 'Stache
  • Duchess Kate wore Roland Mouret to the ‘Top Gun’ premiere: sleek or boring?
  • “Gisele Bundchen breaks down some of her most iconic looks” links
  • Marion Cotillard Wears Shorts to 'Brother & Sister' Premiere During Cannes Film Festival
  • Jessica Chastain Reunites With Oscar Isaac For 'Scenes From A Marriage' Event in NYC
  • Four 'Saturday Night Live' Cast Members Are Leaving After the Season Finale on May 21
  • Tilda Swinton & Idris Elba Generate Oscar Buzz at Cannes with 'Three Thousand Years of Longing'
  • Let's Talk About Sex

Most Recent

  • Dave Chappelle’s alleged attacker charged with attempted murder

    Dave Chappelle’s alleged attacker charged with attempted murder

  • Tom Daley and Dustin Lance Black almost missed son’s birth

    Tom Daley and Dustin Lance Black almost missed son’s birth

  • Ousted Rep. Madison Cawthorn Calls For ‘Dark MAGA’ To Rise Up, Take Over Political Right

    Ousted Rep. Madison Cawthorn Calls For ‘Dark MAGA’ To Rise Up, Take Over Political Right

  • U.S. Justice Department releases $5 million for hotlines to report hate crimes

    U.S. Justice Department releases $5 million for hotlines to report hate crimes

  • Monkeypox Gay Cases Rise; Europe Hits 100 Total; Triggers Emergency WHO  Monkeypox Meeting; Symptoms Mild; Spain Connects Monkeypox virus, Sauna

    Monkeypox Gay Cases Rise; Europe Hits 100 Total; Triggers Emergency WHO Monkeypox Meeting; Symptoms Mild; Spain Connects Monkeypox virus, Sauna

  • Massachusetts identifies first 2022 U.S. case of monkeypox infection

    Massachusetts identifies first 2022 U.S. case of monkeypox infection

  • 25-30 Cases Of Rare Monkeypox Reported in UK, Portugal; Reported Predominantly Among Gay, MSM; Somewhat Treatable with Smallpox Vaccine;

    25-30 Cases Of Rare Monkeypox Reported in UK, Portugal; Reported Predominantly Among Gay, MSM; Somewhat Treatable with Smallpox Vaccine;

Most Commented

Social

Twitter @tlrd | Facebook | Instagram @tlrd
  • Advertise
  • Contact Us
  • About Towleroad
  • Towleroad on Social Media
  • Privacy Policy

Copyright © 2022 · Log in